Department of Biochemistry and Biotechnology, Faculty of Medicine and Health Sciences, University RoviraiVirgili (URV), Reus, Spain. IISPV, Institute of Health Pere Virgily, Reus, Spain. CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. SAGESSA, ABS Reus V. Centre d'Assistència Primària Marià Fortuny, Reus, Spain. ABS Alt Camp Oest. Centre d'Atenció Primària Alcover, Spain. Tarragona-Reus Research Support Unit, Jordi Gol University Institute for Primary Care Research, Tarragona, 43202, Spain. Department of Psychiatry, Radboudumc, Cognition and Behaviour, Donders Institute for Brain, Nijmegen, GA, 6525, The Netherlands. Department of Human Genetics, Radboudumc, Cognition and Behaviour, Donders Institute for Brain, Nijmegen, GA, 6525, The Netherlands.